Ointment psoriasis - an ointment effective for the treatment of psoriasis?

Persons living with a diagnosis of "psoriasis", they do not know first-hand how much depends on the correct choice of the drug. This disease will not forgive the errors of treatment and negligence to their health. An important role in the fight against the symptoms of psoriasis are playing well-chosen external therapy and timely started treatment. A key principle in the choice of a treatment regimen, especially in the early stages of the development of psoriasis, is the principle of "do no harm" — the treatment should not affect the health of the skin, causing the occurrence of unwanted consequences in the shape of atrophy of the skin or of a withdrawal syndrome. After all, the main goal of therapy is to extend the periods of rest and the health of the skin without sudden and painful relapses and exacerbations.

ointment psoriasis

Hormonal ointment psoriasis: cure or kill?

Common of a group of external funds for the treatment of psoriasis are ointments of special hormones. These substances have the property of inhibiting the activity of the immune system, reducing inflammation. Therefore, when in exacerbations of severe psoriasis prescribe systemic steroids — in the form of tablets or injections. However, this approach is fraught with severe side effects: the hormone therapy changes the background of the body, and the cancellation of drugs can cause malfunction of the endocrine system and the cardiovascular system.

Topical steroids (external hormonal funds) in part without the hazardous properties of system of drugs, hormone-based: the effect is manifested only at the site of application. The advantage is the rapidity of the action: after a few minutes after the application of the sick stress reduction of pruritus, and in the next few days is greatly reduced redness in the area of psoriatic platelets, stops their growth and scaling.

However, unfortunately, the side effects are also topical steroids — and no less serious: a cause of the decline of immunity to the site of application, the skin thins, and you screen, you run the risk of accession secondary infection. This is, without doubt, complicates the treatment. The most serious consequence of topical applications of steroids is the development of dependence. In consequence of other means (and topical steroids) already stop helping, causing alternating, sometimes stronger relapse after discontinuation of the drug. That's why the sale of topical steroids in Europe and in the UNITED states without a prescription is prohibited. Independent and uncontrolled use of these funds, belonging to the category powerful, it is unacceptable.

It is important to know! Addison's disease — a condition that develops due to prolonged intake of corticosteroid medicines. In response to the hormonal therapy the adrenal glands, stop by just to produce cortisol and other steroids, which manifests itself with symptoms such as muscle weakness, loss of appetite and weight, decline blood pressure, dehydration, a rapid heartbeat and the constant feeling of anxiety. In Addison disease, the doctors are not always able to restore the function of the adrenal glands, for which the patients for the whole of life prescribe hormone therapy.

Most of the funds on the basis of topical steroids is inexpensive and sold without prescription so the cases of abuse of this type of treatment of psoriasis often. In the meantime, dermatologists recommend not to use steroids local with large (more than 20% of the surface of the skin) areas of loss, but also to apply those funds to the sensitive areas of the body — face, neck, folds of skin and place of diaper rash. It is desirable, and not to abandon the idea to apply hormonal ointments and creams without the appointment of a medical doctor: it is able to reduce the effect of the basic treatment, harm to health and cause a heavy attack aggravation of the psoriasis.

Often hormonal creams and ointments are made on the basis of the following substances:

  • betamethasone;
  • hydrocortisone;
  • mometasone;
  • methylprednisolone;
  • triamcinolone;

The traditional method of non-hormonal ointments for the treatment of psoriasis: will not be worse and better?

Given the serious side effects of hormone creams and ointments, many patients prefer to treat psoriasis with the help of less "aggressive" of drugs. Some of them are a heritage of traditional medicine and traditional recipes for the treatment of the skin, which are very popular in the past.

The advantages of a traditional treatment without hormones of psoriasis should include comparison with the means of safety, cost-effectiveness and lack of serious side effects. The disadvantages of the different (often low) degree of efficiency and, in some cases, allergic reactions that develop in patients to components of this or any other means.

the signs of psoriasis
  • Naphthalan, ichthyol, skin, an ointment of tar — have an anti-inflammatory effect and antiseptic. However, some of them can not apply in the progressive stage of psoriasis and in the squares larger losses, while others (for example, tar ointment, have a certain effect, then it is not advisable to combine with light therapy. In addition, the extended use of these funds increases the probability of developing cancer of the skin. Traditional farms also have quite strong smell and can get dirty clothes, in respect of which are not very convenient to use.
  • Special substances have anti-inflammatory action and antimicrobial, cause reinforced exfoliate the dead cells, which accelerates the healing process of psoriatic platelets. Among the possible side effects — the risk of inflammatory reactions, burning sensation and pigmentation of healthy skin surrounding (the colour of healthy skin and hair brown color).
  • Natural medicine (ointments and creams based on aloe vera, elecampane, celandine, sage, and other herbs) are anti-inflammatory and healing actions, they inhibit the development of skin infections. Aid in the treatment of psoriasis, by integrating the effect of the basic treatment.
  • Moisturizing baby creams and oils in cosmetics) may also be useful in the treatment of psoriasis and help combat the dryness and feeling of skin tension. Their use in combination with medicines that increase the effect of the therapy.

A method of non-hormonal ointments and creams with a marked therapeutic effect: it has been demonstrated clinically

We also highlight a group of drugs which are not hormonal that is effective in the local treatment of psoriasis has been confirmed in clinical studies. Unlike ointments and creams from the previous group, the mechanism of action of these drugs has been studied in the minimum details. They have the advantage as the undisputed first-hormonal means of communication with the most high-profile yet. However, in the treatment of these means must clearly comply with the instructions for use and to know about possible contraindications.

  • Pimecrolimus has high anti-inflammatory activity. However, it is necessary to know that if bacterial or fungal defeat of the skin, application of funds on the basis of pimecrolimus only recommended after healing of the infection. When uncontrolled use of pimecrolimus may cause immunosuppression locally to the skin (suppression immunity), which increases the risk of accession secondary infection, the affected areas of the skin. Therefore, in the UNITED states, for example, pimecrolimus is recommended only as a drug of "second-line" treatment, that is, only in the absence of the effect of other therapy tools. Pimecrolimus banned the use of children up to two years.
  • Kaltsipotriol is a synthetic analogue of vitamin D3. Its action is based on an increase in the level of calcium in the cells of the skin, which normalizes their speed of division, and favors the resorption of psoriatic platelets. Why kaltsipotriol is the hormonal means, that after a series of biochemical reactions is transformed into the hormone metabolite calcium exchange), there are a number of constraints on its use. In particular, kaltsipotriol does not apply when the defeat more than 30% of the surface of the skin because of the risk of hypercalcemia. The latter can cause a disorder of the heart rhythm, and muscle cramps. It is not recommended to apply kaltsipotriol sensitive areas of skin (face, neck, folds). The funds on the basis of this active ingredient have age limits. Kaltsipotriol is also not suitable as an aid in the case of treatment with the method of phototherapy, because under the action of UV rays, causes photosensitization and leads to the development of the burn of the skin.
  • The zinc pyrithione. Because of proven efficacy and safety of the treatment, medicines for the treatment of psoriasis on the basis of this active ingredient can be attributed to the category of " funds "in the middle". Zinc is a organic and natural medication for the treatment of diseases of the skin. Its concentration in a healthy human epithelium is about 20% of the total content of the body, and the shortage of this precious metal is accompanied by a variety of lesions of the skin and damage the healing of wounds. Drugs that target zinc (zinc pyrithione) have a complex of specific properties (anti-inflammatory, anti-bacterial, anti-fungal), help reduce the itching of the skin, promotes the production of ceramides (lipids) in the skin, which leads to rebuild its barrier function. Tools zinc pyrithione activate the so-called apoptosis (natural programmed death) pathologically altered cells of the skin and the cells of inflammation, and then by activating the natural renewal of skin cells, reducing flaking and eliminating causing psoriatic plaques. Research has shown that it is active zinc has comparable transport efficiency and good safety profile, as it is not absorbed from the surface of the skin, is not irritating and harmful effect.

Ointment or cream?

Many of these drugs are available in ointment form, and in cream form. How to choose the most appropriate form?

  • Ointments have the most dense and oily texture, which allows of the drug function a long time, to be on the surface of the skin, especially if applied under the bandage.
  • The cream has a soft consistency, easy to apply and fast absorption, thanks to which it can be applied, leaving the skin open, not making use of bandages and is not afraid to stain your clothes or hands. As a general rule, the cream has a pleasant smell, which is also important during the daily application.
  • Unlike ointment, cream, and, to a lesser extent, is an irritant, so more suitable for the application on the face, the flexion surface of the joints, the areas with high sensitivity. The ointment is not suitable for application on damp areas of the affected skin with liquid detachable. Cream, in this sense, more versatile.
  • Traditionally ointment psoriasis are presented more broadly, however, this imbalance is gradually lined up — the market appears more and more new forms of medicinal products in the form of creams, gels and aerosol, easy to apply and is particularly suitable for the application on hard to reach areas (for example, on the scalp).
the treatment of psoriasis

Looking for a balance between price and quality

Let's try to summarize the information in the form of a table:

Drug group

Active ingredient

The action

The possible limitations and side effects

Hormonal creams and ointments

Betamethasone

Have anti-inflammatory properties, allergic (including anti-itching), and decongestant action. Hydrocortisone-a, methylprednisolone, and other means also have a certain action (overwhelming the local immunity of the skin).

1. It is not recommended long-term (for more than 5 days) and often. 2. Can trigger the development of local complications:

  • discoloration and violation of the metabolic processes of the skin;
  • the withdrawal syndrome;
  • the immunosuppressive action can lead to membership of the secondary infections of the skin.
  • Is contraindicated:
  • for use in sensitive areas of skin (face, neck, folds);
  • large areas of losses (more than 30% of the skin).

Mometasone

Hydrocortisone

Glucocorticoid tool

Methylprednisolone

Triamcinolone

Non-hormonal form of traditional media

  • Oil
  • The sulfur
  • Ichthyol
  • Fat
  • Tar

Have an anti-inflammatory effect and antiseptic.

  • They have quite low efficiency and do not act on the bacterial-fungal agents (when you connect the secondary infection on the skin).
  • Inconvenient for the application (applied several times per day, often under the blindfold, require very long treatment schemes, dirty linen for the house and have an unpleasant smell).
  • Can cause irritation and dryness of the skin and allergic reactions.

Active substance the active exfoliate the dead cells from the surface of the skin:

  • dithranol
  • sulfur and salicylic acid

Cause reinforced exfoliate dead cells, have anti-inflammatory action and antimicrobial.

Can cause inflammatory reactions, burning sensation and pigmentation of healthy skin surrounding (the colour of healthy skin and hair brown color).

Non-hormonal drugs

Pimecrolimus

Possesses anti-inflammatory activity.

  • It is not recommended to use in case of bacterial or fungal lesions of the skin.
  • Can cause immunosuppression locally to the skin (reducing immunity).
  • It is contraindicated in children up to two years.

Kaltsipotriol

It is a synthetic analogue of vitamin D3, promotes the resorption of psoriatic platelets.

  • It is not recommended:
  • apply with the defeat of more than 30% of the surface of the skin because of the risk of hypercalcemia;
  • apply on the sensitive areas of skin (face, neck, folds, scalp);
  • combine with the method of phototherapy in relation with the risk of skin burns.
  • It is contraindicated for patients below the age of six years.

Zinc pyrithione

Has full action:

  • anti-inflammatory drugs;
  • antipruritic;
  • protection against the adhesion of infection;
  • activating the natural renewal of the epithelial cells to resolve psoriatic platelets;
  • the recovery of the barrier function of the skin.
  • It has a high safety profile.
  • Has no limits on the duration and area of application.
  • It has no side effects (except in cases of individual intolerance).
  • It is allowed for the use of children in a year.

Psoriasis is a chronic disease, so each patient is important to find the best medication that combines the high efficiency and minimal side effects (and, preferably, at a good price). And remember: before starting to apply any tool, read the instructions, all the possible contraindications and side effects, and also be sure to consult with your family doctor. This will help you get the best results without compromising health.

ointment against psoriasis

Promptly started treatment for psoriasis is a key factor of success. Remember that the sooner you start to treat the psoriasis, the less likely it is that it is necessary to resort to "heavy artillery" — hormonal means.

03.10.2018